A 17-year-old girl started fluoxetine 2 weeks ago for depression. Her mood is slightly better, but she now reports passive suicidal thoughts without a plan or intent.  

A 33-year-old patient with depression and obesity is concerned about weight gain with antidepressants. Which medication would be the most appropriate to minimize weight gain and potentially promote weight loss?

A provider is considering starting bupropion for depression given its favorable side effect profile regarding sexual dysfunction and weight gain.Which patient has an absolute contraindication to bupropion?

A 42-year-old patient with MDD and chronic insomnia reports difficulty initiating and maintaining sleep. You want to select an antidepressant that may also improve sleep. Which is the best option?

A 45-year-old woman is prescribed zolpidem for insomnia. What is the most important instruction to give her?

A patient develops tardive dyskinesia from long-term antipsychotic use. Which of the following medications is FDA-approved for the treatment of tardive dyskinesia?

A 32-year-old woman taking lamotrigine for bipolar disorder develops a new rash on her body. She has no fever or other symptoms. What is the best next step?

A 25-year-old patient presents to the ED with sustained neck contraction and upward eye deviation shortly after starting a high-potency antipsychotic. What is the best immediate treatment?

A patient on clozapine presents with fever, sore throat, and malaise. Labs show ANC of 900. What is the best next step?

A 52-year-old patient on olanzapine for schizophrenia has gained 20 pounds and developed elevated fasting glucose. What is the best next step?