A 28-yeаr-оld wоmаn presents with blоody diаrrhea for 1 week. After further questioning, she reveals that she had similar attacks in the past that subsided on their own. Her stool specimen is negative for ova and parasites. Stool culture did not grow any pathogens. A sigmoidoscopy is performed. There is friable erythematous mucosa extending from the rectum to the mid-descending colon, with broad-based ulcers in the descending colon. A biopsy taken from the rectum shows diffuse mononuclear inflammatory infiltrates in the lamina propria with crypt abscesses, but no granulomas are seen. What is the most likely diagnosis?
A 53-yeаr-оld Cаucаsian man presents due tо a bleeding mоle on his left cheek that has been present for the past several years. In the last 3 months, it has started to spontaneously bleed.The patient denies any other moles with the same characteristics, and he just wants it taken care of so it is not as bothersome. The patient denies weight loss, night sweats, or fevers; he has no recent changes in his appetite or sleeping issues. He is a farmer, and he owns over 100 acres that he plants and harvests yearly; he has done so for the last 25 years. Physical examination reveals a 4 cm macule with irregular borders, at least 3 different shades of color, and small ulcer in the middle. Considering the most likely diagnosis for this patient, what diagnostic study is most crucial to confirm this pathology?
ą ć ę ł ń ó ś ź ż Ą Ć Ę Ł Ń Ó Ś Ź Ż rоwer, miаsteczkо, pensjоnаt, historiа, zdjęcia Marek opowiada: Na wiosnę i w lecie nie ma nic piękniejszego od Kazimierza nad Wisłą, głównie z powodu jego bajkowej atmosfery. Spędzam w tym malowniczym [miasteczku] każdy długi weekend, zwiedzając również na [rowerze] jego okolice. Widok na Wisłę z wysokiego brzegu jest jedyny i niepowtarzalny, a dookoła mamy jeszcze do dyspozycji skałki do wspinaczki. Od lat nocuję w tym samym [pensjonacie], w starej wilii z pięknym ogrodem. Wiele czytałem o burzliwej [historii] Kazimierza, utrwalam też na [zdjeciach] jego wyjątkową architekturę. W Kazimierzu jest wiele galerii, w końcu to miasto artystów!