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    One thousand compounds were tested in both ferrets and h…

Posted byAnonymous July 9, 2021September 26, 2023

Questions

    One thоusаnd cоmpоunds were tested in both ferrets аnd humаns for their ability to induce a specific response at a defined dose. All compounds were scored as either positive (produces response) or negative (does not produce response) in both species. The results of the experiment are presented below, where each cell of the 2x2 matrix is the number of compounds in thatcategory. For example, 138 of the 1000 compounds tested were negative in ferret and positive in human. Analyze and describe the ability of the ferret response assay to predict the human response over this set of compounds by determining the sensitivity specificity positive predictive value negative predictive value and overall accuracy of the ferret assay Use units of % for all parameters. Answers must be included in the box below. Please show all your work using scrap paper to perform your  calculations. To receive full credit, you must upload a photo of all work performed on scrap paper to Canvas.

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