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Question 1 (5 points) The titration curve for Histidine is s…

Posted byAnonymous August 6, 2025August 6, 2025

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Questiоn 1 (5 pоints) The titrаtiоn curve for Histidine is shown here.    Question 1 refers to this titrаtion curve. Answer the following questions with the letter on the curve thаt signifies the correct position on the curve. (1 pt. each)  Image Description  The graph titled “Histidine Titration” illustrates the titration curve of histidine, depicting the relationship between pH and the equivalents of OH⁻ (hydroxide ions) added. The x-axis represents the equivalents of OH⁻ added, ranging from 0 to 3.0, and the y-axis represents the pH, ranging from 0 to 12. Key points labeled A, B, C, D, E, and F mark significant stages in the titration process. Point A, at approximately pH 2, corresponds to the fully protonated form of histidine. Point B, around 0.5 equivalents OH⁻ and pH 3, represents the first buffering region where the carboxyl group (COOH) is being deprotonated to COO⁻. Point C, at around 1.0 equivalents OH⁻ and pH 6, indicates the first equivalence point where the carboxyl group is fully deprotonated. Point D, around 1.5 equivalents OH⁻ and pH 8, marks the second buffering region where the imidazole side chain begins deprotonation. Point E, at around 2.0 equivalents OH⁻ and pH 9, represents the second equivalence point where the imidazole side chain is fully deprotonated. Finally, Point F, at around 3.0 equivalents OH⁻ and pH 11, indicates the stage where the amino group is deprotonated. 

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