Antibody class switching requires appropriate cytokine stimulation.  What cytokines are most important for driving B cell class switching to…  IgG that is capable of activating complement? IgE?

Regarding the tissue represented in the figure, the identity of the region labeled A is…

What is a molecule that can be expressed on an APC and that can provide costimulation to a T cell?

To generate effector cells from a naive mature T cell, activation signals 1 and 2 must be received from a professional APC, but then a third signal is also needed.  Please label your answers (1-2). 1. In what form is this third signal delivered?   2. What is the function of this third signal?

The structures of IgM and IgA contain a component that no other antibodies contain.  This structural component provides for specific binding to a receptor.  Please label your answers (1-4). 1. What is the structural component? 2. What is the receptor that can be bound by the antibodies due to the structural component, above? 3. Binding to this receptor facilitates what to be done with these antibodies (something that is not done to any other antibodies)? 4. In what tissue is this receptor most commonly found?

Conventional dendritic cells (cDC) have two major developmental states.  One is the default state (immature), and the other is a state into which they mature.   For the questions below, please number your answers. 1. What is the global function of immature cDCs? 2. What would trigger maturation of a cDC? 3. What is the global function of mature cDCs?

There are two forms of combinatorial diversity.  One involves V(D)J recombination.  What is the other form?

Blood lymphocytes are either CD3+ or CD3-.  Which of these populations is the largest by percentage?

Regarding the antibody shown above (Please label your answers 1-4)… 1. How many heavy chains does it contain?2. In any one of those heavy chains, how many CDRs will be found?3. Can this type of antibody be produced without T cell help?4. When this type of antibody is produced by a cell, what other type of antibody is also produced by that cell, even if only in small amounts?

The initials of the typist of a Business letter should be in