Chediak Higashi syndrome often develops thrombocytopenia.  This condition, characterized by a low platelet count, contributes to bleeding tendencies observed in these patients. In addition to thrombocytopenia, Chediak-Higashi patients may also experience anemia and neutropenia. The neutrophils exhibits giant, abnormally large lysosomal granules in the cytoplasm.

The following diseases are associated with thrombocytosis: primary myelofibrosis, essential thrombocythemia, chronic myelocytic leukemia, and polycythemia vera

Both Bernard Soulier and VWD have issues of inadequate binding of platelets to the endothelial system.   Bernard Soulier is lacking in __________ and VWD is lacking in ___________

Which of the following statement is true with vitamin K deficiency

What is thrombophilia? a. predisposition to thrombosis secondary to a congenital or acquired disorder b. inappropriate triggering of the plasma coagulation system c. a condition in which clots form uncontrollably d. inadequate fibrinolysis

Which of the following is best describing of Bernard Soulier Syndrome A. Presence of giant platelets, thrombocytopenia, normal PFA, normal VWF activity, PT and APTT normal, normal platelet aggregation. B. Normal PT and APTT; presence of giant platelets and thrombocytopenia; absent GPIB receptor by flow cytometry C. Normal platelet count; some large platelets; PT and APTT prolonged; prolonged bleeding time and PFA D. Thrombocytosis; abnormal platelet aggregation with ADP, Collagen, and Epinephrine; normal ristocetin.

Patient with Wiskot Aldrich Syndrome has thrombocytopenia because

Which the following test results is normal in a patient with classic von Willebrand disease?

All of the following are pathophysiology of  thrombocytopenia: 1. abnormal platelet production 2. abnormal distribution of platelets 3. increased platelet production 

The best laboratory assay to predict liver disease coagulopathy is