An APTT and PT are requested on a patient scheduled for emergency surgery. On an optical density clot detection system, normal and abnormal controls for both tests are within range, but the patient’s results are extremely prolonged. The patient’s tests have been performed in duplicate, but there is sufficient plasma, which is dark amber, to repeat the tests. What is the best course of action to follow?

Referring to the figure below, the isoalloxazine ring present in the cofactor known as FAD is reduced to a semiquinone by addition of an H+ and electron.   As shown, the negatively charged oxygen in the semiquinone 

Which of the following represents a normal Activated Partial Thromboplastin Time (APTT)?

Escherichia Coli infections have been associated with which of the following?

Which of the following has an autosomal dominant inheritance pattern?

Coagulation testing for a Prothrombin time requires that the plasma specimen be tested within:

Which factor listed below is restricted to the extrinsic system?

Platelets are produced in the:

Which factors are measured by both the PT and APTT?

Referring to the excerpt below, which is from a paper published by Dr. Haley Ball, former PhD student in the Couch research lab, answer the following question.   In the crystal structure, several amino acids are seen to surround the inhibitor (the inhibitor is denoted as “FR” in the image), including D159, E161, S160, E239, K236, N235, S230, S191, and W220 (the notation used is the single letter amino acid followed by its location in the amino acid sequence, relative to the #1 position at the N-terminus of the protein). At physiological pH, the amino acids with charged side chains located in the FR binding site are: