A 40-year-old patient presents to your outpatient clinic with fever, diffuse headache, photophobia, and neck discomfort. Neurologic screening is nonfocal. You plan a focused bedside examination to evaluate for meningeal irritation. Which maneuver is most appropriate to perform now?

A 65-year-old right-handed man reports a long-standing action tremor of both hands that worsens with stress and improves slightly with small amounts of alcohol. It now interferes with writing and using utensils. Neurologic examination is otherwise normal; there is no rigidity, bradykinesia, gait change, or resting tremor. He has moderate persistent asthma on an inhaled corticosteroid–long-acting beta-agonist, resting heart rate 56 beats per minute, and well-controlled hypertension. Which treatment is most appropriate to start in the outpatient clinic?

A 47-year-old with an inversion ankle sprain has normal radiographs and intact neurovascular exam. He requests opioids. What is the best approach?

A 60-year-old man has an acute onset of severe pain, redness, and swelling at the great toe joint after a large meal and alcohol. What is the most appropriate initial therapy?

A 55-year-old man has erectile difficulties for one year. He has hypertension and hyperlipidemia. Which initial evaluation step is most appropriate?

A 28-year-old with migraine history reports a sudden “worst headache of life,” different from prior attacks. What is the next best step?

A 31-year-old woman has unilateral painful vision loss and a relative afferent pupillary defect; she reports past transient neurologic episodes. Which diagnosis should be strongly considered?

A 58-year-old man has a painless scrotal swelling that transilluminates. He can feel the testis separate from the swelling. What is the most likely diagnosis?

A 64-year-old with knee osteoarthritis has posterior knee fullness and discomfort; ultrasound shows a popliteal cyst. He has no redness or severe pain. What is the best management?

A 72-year-old woman has new headache, scalp tenderness, jaw claudication, elevated inflammatory markers, and sudden visual changes. What is the most appropriate immediate management?