CDKs are the workhorses of the cell cycle machinery. To function properly, CDKs pair with cognate cyclins, which in turn, regulate which two CDK properties/activities?

The epithelia is the site of origin for which type of cancer

How can oncogenic Ras signaling reduce anoikis?

Oncogenic mutations in ras are most often the result of

Which of the following is NOT true of the Src protein?

Briefly describe the mechanism by which NF1 protein (neurofibromitosis 1) can down-regulate signaling by receptor tyrosine kinases.

In addition to tyrosine kinase receptors, there are yet other receptor types that mammalian cells use to communicate with their environment. Which of the following statements about these other types of receptors is TRUE?

In cells infected with simian sarcoma virus, the sis oncogene causes the cells to release increased amounts of Sis protein, which is recognized by PDGF-receptor molecules on the cells surface. This type of signaling loop is an example of __________ signaling?

In the revised Ames test, Bruce Ames mixed chemicals with homogenized rat liver prior to adding them to bacteria to assess their mutagenicity. What was the purpose of this step of the experiment?

Briefly describe the difference between euploid and aneuploid and indicate which is more likely observed in cancer cells.