Fabrication/Manufacturing (Please number your responses to e…
Fabrication/Manufacturing (Please number your responses to each question): Choose specific materials and state why you would use the chosen materials for this tissue type. (decellularized tissues are not allowed) Does this material degrade? By what method? If not, how will you modify it? Choose a specific method of scaffold fabrication and state why this method synergizes with the needs/functionality of your chosen tissue. State one specific biomolecule (growth factors, cytokines, or hormones that are normally found in the body with this tissue type, and is NOT an ECM protein) that promotes your tissue’s successful regeneration, state why it is important, and state how you will incorporate it into your scaffold. (just stating “added to scaffold” is not enough detail—see drug loading methods and bioconjugation methods from the lectures) State the two most important criteria your scaffold must meet for this specific tissue type. (must be specific to your tissue type—for example both biocompatible and good mass transport are not specific and is therefore not a correct response here) Choose one scaffold design parameter that can be modified to promote your tissue’s successful regeneration, state why it does, and state how you will modify this parameter (i.e., pore size, surface chemistry, topography, etc.). Choose a specific cell type to use with or within your scaffold, state the source of the cell, and why you are choosing it. If you choose to start with stem cells, make sure you specify how you plan to differentiate them into the appropriate cell type, and state what cell type/s you need for your tissue type. Choose a specific bioreactor to encourage successful development of your scaffold and state why the selected tissue and scaffold design benefit from this bioreactor.
Read DetailsAt the beginning of the current year, Monica has tax basis o…
At the beginning of the current year, Monica has tax basis of $130,000 in her interest in Perks, LLC, and her at risk amount is $105,000. Her share of Perk’s current year losses is $150,000, all of which is passive. Monica has a separate investment that generated $90,000 of passive income. Ignoring the excess business loss hurdle, based on this information, how much of Perk’s losses may Monica deduct for the current year?
Read DetailsDarcy is a 40% shareholder in McKinnon, an S corporation. In…
Darcy is a 40% shareholder in McKinnon, an S corporation. In the current year, McKinnon reports ordinary income of $36,000, §179 expense of $10,000, and qualified dividend income of $6,000. McKinnon made a $10,000 distribution to Darcy and Darcy had beginning of the year stock basis of $30,000. Determine Darcy’s ending stock basis.
Read DetailsIn the current year, Chevy Inc. reported the following infor…
In the current year, Chevy Inc. reported the following information:Excess capital losses over capital gains$5,000Book depreciation in excess of tax depreciation$6,200Tax exempt interest income$1,800Which of the following is correct?
Read DetailsLuxor Corporation has nexus in States A and B. Luxor’s curre…
Luxor Corporation has nexus in States A and B. Luxor’s current year information is summarized as follows: State AState BTotalSales$1,080,000$720,000$1,800,000Property Average historical cost1,950,0001,050,0003,000,000Payroll640,000160,000800,000Determine the apportionment factor for State A assuming State A uses a three-factor formula, with sales double weighted.
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