A battery with EMF of 24 V and negligible internal resistanc…
A battery with EMF of 24 V and negligible internal resistance is connected to a resistor network as shown. Before the switch is closed, a current is delivered by the battery. After the switch is closed, a current is delivered by the battery. Find
Read DetailsA RCT compared eptinezumab (a new CGRP antagonist) to topira…
A RCT compared eptinezumab (a new CGRP antagonist) to topiramate for migraine prevention using an NI margin of 0.5 monthly migraine days. The mean decrease in monthly migraine days with eptinesumab was 3.9 days and with topiramate was 4.1 days (mean difference 0.2 days; 95%CI -0.02 to 0.42). Which of the following statements is the best interpretation of the results?
Read DetailsItepekimab was compared to placebo in a RCT for use in patie…
Itepekimab was compared to placebo in a RCT for use in patients with moderate-to-severe atopic dermatitis (i.e. severe skin inflammation and itching). The primary outcome was changes in the Eczema Area and Severity Index (EASI) score which has a minimally clinically important difference of a change in at least 6.6 points. At week 16 in the RCT, itepekimab had a mean decrease in the EASI score of 14.2 points compared to placebo (p=0.12).
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