Which of the following is NOT a criterion used to select candidate genes for QTN identification in the article?

Fine-mapping QTLs typically reduces the confidence interval, leading to more precise QTL identification.

In dairy cattle, which design is most commonly used for QTL detection?

The effective population size (Ne) of cattle has increased over time, similar to human populations.

Question 2 (10 points) Show that the given differential equations is exact or not.  If its exact, solve it directly.  If its not exact, solve it by finding an appropriate integrating factor.

Phenobarbital (Luminal) 45 mg p.o. BID is ordered for a child with seizures weighing 35 lb. The recommended dosage is 6 to 8 mg/kg every 24 hr. in 2 divided doses.True or False: the dosage ordered is safe.  (Prove mathematically) 

Question 4 (10 points) Find the inverse Laplace transform

Provide an example from the article of a mutation in cattle with a moderate-to-large effect on a complex trait and describe its impact.

Question 9 (10 points) Find a general solution  to the following differential equation using the method of variation of parameters.

Question 3 (10 points) The radioactive isotope of a substance, decays at a rate proportional to the amount present at the time  and has a half-life of 3.3 hours.  If 1 gram of this isotope is present initially, how long will it take for 75% of the substance to decay?