Match the error to the expected outcome.  What effect will the following have on the outcome of the sickle solubility test result? 

Spectrin is an example of what type of protein and a defect in it is seen in which condition?

Which is a typical finding in paroxysmal nocturnal hemoglobinuria?

A patient who has blood type AB and is given blood type A would have which of the following: 

Diepoxybutane causes chromosomal breakage in which disorders?

A couple has recently come back from honeymooning in Costa Rica.  They are feeling under the weather, but attributed it to the change in climate.  The husband has now developed a fever that seems to spike in the morning and evenings after dinner.  During his fever episodes, he is suffering from chills and generalized aches all over his body.  Which of the following tests would best confirm this picture?

A patient’s labs show an increased LDH, a decreased haptoglobin, with moderate schistocytes and polychromasia on the peripheral blood smear.  The patient is suffering from: 

Peripheral blood smear review reveals a pancytopenia.  A bone marrow aspirate is performed and the M:E ratio is 3:1, but the overall cellularity of the marrow is decreased.  What conclusions can you make from these findings? 

Which of the following laboratory findings is most consistent with a diagnosis of pernicious anemia? 

A 25 year old man of Filipino descent was evaluated because he was found to be anemic when he attempted to donate blood.  He otherwise had no complaints.  He stated that he is active in sports and feels healthy.  A CBC gave the following results: TEST RESULT REFERENCE RANGE RBC 5.76 x 106/ul 4.5-5.50 X 10^6/ul WBC 3.8 x 103/ul 4-10 x 10^3/ul HGB 10.4 g/dl 13-15 g/dl HCT 35.9 % 35-47% MCV 62 fl 80-100 fl MCH 18.1 pg 27-31 pg MCHC 29 % 32-36% RDW 13.5