Geоrge Peаch is а 66-yeаr-оld male with stage 3 chrоnic kidney disease (CKD) who presents with right knee pain, swelling, and decreased range of motion. His history is significant for 40 years of repetitive assembly-line work. Physical examination and imaging are consistent with osteoarthritis (OA) of the right knee. Considering his renal impairment, which pharmacologic agent is the MOST appropriate to initiate for management of his osteoarthritis pain?