Singer Rihаnnа suffers frоm Eczemа, a chrоnic inflammatоry skin condition that causes rashes, itching, and red inflamed skin. Rihanna hears a clinical trial advertisement on a podcast: “Do you suffer from Eczema? Learn more about our revolutionary new treatment called Mango. In one trial so far, participants reported 90% clearer skin using Mango. Contact Rose Pharmaceuticals today to enroll in this breakthrough trial and see if you qualify.” Rihanna calls because she is desperate to get access to Mango, and she believes that it is the best and newest treatment for Eczema. Rihanna meets with Nurse Betty, the Clinical Research Coordinator at Rose Pharmaceuticals. Assume the Mango clinical trial has been approved by an Institutional Review Board. Betty tells Rihanna, “This trial is looking at the safety and effectiveness of a new topical ointment for Eczema called Mango. In this trial, we will be testing Mango to see how it compares to another treatment already on the market called Cream. There is a potential benefit of experiencing clearer skin and contributing important information to medicine. There are also minor risks, but so far the risks of Mango appear similar to Cream. Would you like to get started?” Rihanna agrees, signs the consent form, and begins participating in the trial. However, it turns out that both Mango and Cream carry a 2% risk of skin cancer. Rihanna develops massive rashes covering her body, is diagnosed with skin cancer while using Mango, and is outraged. Rose Pharmaceuticals insists that Rihanna’s symptoms are not related to Mango, and asserts Mango has already helped millions of participants with their Eczema symptoms. (A) Define the concept of therapeutic misconception. From Rihanna’s perspective, how did therapeutic misconception apply in this case? Explain and elaborate using details from the question and course materials. (B) Adopt either position (choose one side only): From Rihanna’s perspective, explain why the clinical trial for Mango violated principles of human subjects research using at least 3 concepts/ethical principles from course materials. First define the concept, then explain how it applies to Rihanna’s situation. From Rose Pharmaceutical’s perspective, explain why the clinical trial for Mango upheld principles of human subjects research using at least 3 concepts/ethical principles from course materials. First define the concept, then explain how it applies to how Rose Pharmaceuticals conducted the trial.
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