A 5-year-old has morning headaches, vomiting, and lethargy. Exam shows papilledema and abnormal gait. Which diagnostic step should be avoided?

A 17-year-old with a complex chronic condition is planning to graduate high school and start work. The family reports uncertainty about insurance after graduation and difficulty coordinating records between pediatric specialists and a future adult primary care clinician. Which plan best reflects a systems-based approach aligned with the transition framework?

Match the presentation to the most likely diagnosis.

A 9-year-old is recovering from influenza. Today they develop sudden, severe, persistent vomiting followed by confusion and agitation. Parents report giving an over-the-counter medication containing salicylate during the viral illness. Which initial lab finding(s) are most consistent with Reye syndrome and should be prioritized immediately?

A 9-year-old on chemotherapy presents to urgent care with a temperature of 38.6°C and ANC 300. Parents want to “wait and see” because he looks okay. What is the best next step?

A 3-year-old is brought in because a caregiver felt a firm abdominal mass while bathing the child. Vitals show elevated blood pressure. Which mechanism best explains the hypertension commonly seen in Wilms tumor?

A 10-year-old has progressive headaches and visual changes. Parents also report new excessive thirst/urination and early pubertal changes. Which tumor location association best fits these endocrine findings?

Exhibit: A 7-year-old has had two episodes of meningococcal meningitis despite appropriate treatment. Growth is normal. CBC shows normal absolute lymphocyte count. Quantitative IgG/IgA/IgM are within age-based reference ranges. Which next test is most appropriate?

A child diagnosed with Kawasaki disease completed initial treatment and is clinically improving. Which follow-up element is most essential to reduce long-term morbidity?

Match each lab pattern to the most likely diagnosis.