In typical blood vessels, the alpha smooth muscle actin (aSM…
In typical blood vessels, the alpha smooth muscle actin (aSMA) gene is highly expressed in the smooth muscle cell layer but not in the endothelial cells that line the vessels. Compare the aSMA gene in smooth muscle cells and epithelial cells in terms of: A. Likely modifications in the regulatory regions of the aSMA gene in the two cell types. Briefly explain your reasoning. (4 points) B. Likely positions of the aSMA gene in topological associated domains and/or lamina-associated domains in the two cell types. Briefly explain your reasoning. (4 points)
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